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| Drug Class: What is Product Title?> an why is it prescribed? |
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| Caduet is a combination of Amlodipine and Atorvastatin.
Caduet is used to treat high blood pressure or angina (chest pain) that occurs together with elevated levels of cholesterol or triglycerides.
Atorvastatin is in a class of drugs called HMG CoA reductase inhibitors. Atorvastatin blocks the production of cholesterol (a type of fat) in the body.
Amlodipine is in a class of drugs called calcium channel blockers. Amlodipine relaxes (widens) the blood vessels (veins and arteries), making it easier for the heart to pump and reducing its workload.
Caduet may also be used for purposes other than those listed in this medication guide.
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| Drug Mechanism: How does Product Title work? |
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| Caduet contains a dihydropyridine calcium channel blocker (Amlodipine) and a 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor (Atorvastatin).
Amlodipine inhibits the transmembrane influx of calcium ions across cell membranes with a greater effect on vascular smooth muscle than on cardiac muscle, causing a reduction in peripheral vascular resistance and a reduction in blood pressure.
Atorvastatin inhibits HMG-CoA reductase and cholesterol synthesis in the liver and increases the number of hepatic low-density lipoprotein (LDL) receptors on the cell surface, thereby lowering plasma cholesterol and lipoprotein levels.
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| Dosage: How should you take Product Title |
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| Take Caduet tablets by mouth. Swallow the tablets with a drink of water. You can take the tablets with or without food.
Do not significantly increase grapefruit juice intake while taking Caduet, or avoid grapefruit juice if possible. Take your doses at regular intervals. Do not take Caduet more often then directed. Do not stop taking except on your prescribers advice.
Adults
The starting dose of Caduet is combination of Amlodipine 5mg and Atorvastatin 10mg.
Elderly patients over 65 years old may have a stronger reaction to Caduet and need smaller doses.
Children
Caduet is not recommended for use in children.
If you miss a Caduet dose
If you miss a dose of Caduet, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses of Caduet.
Caduet Overdose
Caduet overdose may lead to serious consequences. Seek medical emergency immediately.
Caduet Storage instructions
Keep Caduet out of the reach of children in a container that small children cannot open.
Store Caduet at controlled room temperature at 25 degrees C (77 degrees F). Short periods of storage at 15 to 30 degrees C (59 to 86 degrees F) are permitted.
Preparations: Tablet- Amlodipine 5mg+ Atorvastatin 10mg
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| Possible food and drug interactions when taking Product Title |
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| Do not take Caduet with any of the following
•alfuzosin
•alcohol-containing beverages
•antiinflammatory drugs (NSAIDs, such as ibuprofen)
•barbiturates (examples: phenobarbital, butalbital, primidone)
•antacids
•birth control pills
•bosentan
•carbamazepine
•danazol
•digoxin
•grapefruit juice
•herbal or dietary supplements such as ginger, gingko biloba, ginseng, hawthorn, ma huang (ephedra), melatonin, St. Johns wort, went yeast
•imatinib,
•local anesthetics or general anesthetics
•medicines for fungal infections (examples: fluconazole, itraconazole, ketoconazole, voriconazole)
•medicines for high blood pressure
•medicines for treating HIV infections
•medicines that suppress your immune response (cyclosporine)
•medicines to lower cholesterol or triglycerides (examples: colestipol, fenofibrate, gemfibrozil, niacin)
•medicine used to stop early pregnancy
•medicines for prostate problems
•medicines for seizures (carbamazepine, oxcarbazepine, phenobarbital, phenytoin, primidone, zonisamide)
•nefazodone
•nicardipine
•rifampin, rifabutin, or rifapentine
•pioglitazone
•some antibiotics (clarithromycin, erythromycin, telithromycin, troleandomycin)
•some medicines for heart-rhythm problems (amiodarone, diltiazem, verapamil)
•some medicines for depression or mental problems (fluoxetine, fluvoxamine, nefazodone)
•diuretics
•yohimbine
•zafirlukast
•zileuton
Tell your prescriber or health care professional about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way Caduet works. Check with your health care professional before stopping or starting any of your medicines.
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| Special information on Product |
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| Most Important Fact about Caduet
Do not stop taking Caduet without first talking to your doctor. It may be necessary to continue to take Caduet on a long-term basis.
Caduet precautions if you are pregnant or breastfeeding
The safety of Caduet in pregnancy has not been established. Caduet should not be taken by women who are pregnant, and women who could get pregnant should use an effective method of contraception to prevent pregnancy while taking Caduet. Seek further medical advice from your doctor.
There is no information available about the safety of Caduet during breastfeeding. For this reason, Caduet should not be used during breastfeeding. Seek medical advice from your doctor.
Special warnings about Caduet
Visit your prescriber or health care professional for regular checks on your progress. You will need to have regular tests to make sure your liver is working properly.
Tell your prescriber or health care professional as soon as you can if you get any unexplained muscle pain, tenderness, or weakness, especially if you also have a fever and tiredness.
Caduet contains a cholesterol lowering agent (Atorvastatin), but is only part of a total cholesterol-lowering program. Your physician or dietitian can suggest a low-cholesterol and low-fat diet that will reduce your risk of getting heart and blood vessel disease. Avoid alcohol and smoking, and keep a proper exercise schedule.
Check your blood pressure and pulse rate regularly; this is important while you are taking Caduet. Ask your prescriber or health care professional what your blood pressure and pulse rate should be and when you should contact him or her.
You may feel dizzy or lightheaded. Do not drive, use machinery, or do anything that needs mental alertness until you know how Caduet affects you. To reduce the risk of dizzy or fainting spells, do not sit or stand up quickly, especially if you are an older patient. Avoid alcoholic drinks; they can make you more dizzy, increase flushing and rapid heartbeats.
Do not suddenly stop taking Caduet. Ask your prescriber or health care professional how you can gradually reduce the dose.
If you are going to have surgery, tell your prescriber or health care professional that you are taking Caduet.
Why Caduet should not be prescribed?
Caduet should not be used if you suffer from cardiogenic shock (failure of the heart to maintain adequate circulation of blood), aortic stenosis (narrowing of the main artery coming from the heart) or unstable angina (angina not well controlled by medical treatment)
Caduet should not be used if you are allergic to one or any of its ingredients. Please inform your doctor or pharmacist if you have previously experienced such an allergy.
If you feel you have experienced an allergic reaction, stop using Caduet and inform your doctor or pharmacist immediately.
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| Product Title side effects |
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| More common side effects of Caduet may include:
• diarrhea
• drowsiness
• facial flushing
• gas
• headache
• joint pain
• nausea,
• vomiting
• stomach upset or pain
• tiredness,
• weakness or fatigue
Less common or rare side effects of Caduet may include:
• dark yellow or brown urine
• decreased urination, difficulty passing urine
• fainting spells,
• dizziness, or
• lightheadedness
• fever
• irregular heartbeat, chest pain, palpitations
• muscle pain, tenderness, cramps, or weakness
• redness, blistering, peeling or loosening of the skin, including inside the mouth
• skin rash, itching
• swelling of legs or ankles
• unusual tiredness or weakness
• yellowing of the skin or eyes
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Drug Class: What is Product Title?> an why is it prescribed?
