Drug Class: What is Probenecid and why is it prescribed?
Probenecid Mechanism: How does Probenecid work?
Probenecid Dosage: How should you take Probenecid
Possible food and drug interactions when taking Probenecid
Special information on Probenecid
Probenecid side effects
|Drug Class: What is Probenecid and why is it prescribed?|
|Generic Probenecid is used in the treatment of chronic gout or gouty arthritis. These conditions are caused by too much uric acid in the blood. Generic Probenecid works by removing the extra uric acid from the body. Generic Probenecid does not cure gout, but after you have been taking it for a few months it will help prevent gout attacks. Generic Probenecid will help prevent gout attacks only as long as you continue to take it.
Generic Probenecid is also used to prevent or treat other medical problems that may occur if too much uric acid is present in the body.
Generic Probenecid is sometimes used with certain kinds of antibiotics to make them more effective in the treatment of infections.
|Probenecid Mechanism: How does Probenecid work?|
|Gout occurs when excessive amounts of uric acid build up in the blood. This leads to the formation of uric-acid-based crystals that are deposited in the joints, causing inflammation and leading to the sharp, excruciating pain of a gout attack. Generic Probenecid works on the kidneys to increase the rate at which uric acid is excreted. In gout, crystals of uric acid form in the joints and cause the characteristic pain and inflammation. By lowering the levels of uric acid, gout can be prevented. Generic Probenecid also slows the body\'s removal of antibiotics, thus increasing their levels in the blood and prolonging their duration of action.|
|Probenecid Dosage: How should you take Probenecid|
|For treating gout or removing uric acid from the body:
250 mg (one-half of a 500-mg tablet) two times a day for about one week, then 500 mg (one tablet) two times a day for a few weeks. After this, the dose will depend on the amount of uric acid in your blood or urine. Most people need 2, 3, or 4 tablets a day, but some people may need higher doses.
For helping antibiotics work better:
If you miss a Generic Probenecid dose
Generic Probenecid Overdose
Symptoms of Generic Probenecid overdose include
Generic Probenecid Storage instructions
Generic Probenecid Preparations: Tablet - 500mg
|Possible food and drug interactions when taking Probenecid|
Generic Probenecid increases the blood levels of the following medicines, leading to an increased risk of side-effects or toxicity:
It is especially important to avoid using Generic Probenecid together with aspirin or salicylates. The effects of Generic Probenecid are reduced considerably in the presence of salicylates (e.g. aspirin).
|Special information on Probenecid|
|Most Important Fact about Generic Probenecid
It may take several months before you see the full effect of Generic Probenecid. Do not stop taking except on your prescriber or health care professional\'s advice. Generic Probenecid is only effective if you keep taking it regularly even if you have an attack of gout. Your prescriber or health care professional will prescribe other tablets to treat an acute attack.
Generic Probenecid precautions if you are pregnant or breastfeeding
Breastfeeding mothers should use Generic Probenecid with caution, and only if the expected benefit to the mother is greater than any possible risk to the baby. Seek medical advice from your doctor.
Special warnings about Generic Probenecid
Alcohol can increase the amount of uric acid in your body and aggravate gout. Alcohol can also make Generic Probenecid less effective. Avoid alcoholic drinks.
Drink 10 or more full glasses of water a day while taking Generic Probenecid. This will help to prevent formation of kidney stones and other possible kidney problems by removing excess uric acid. Generic Probenecid works best when the urine is alkaline (non-acidic). Ask your prescriber or health care professional about which foods or juices to avoid, and about other foods, beverages or antacids that may help to make the urine alkaline.
Generic Probenecid can interfere with the results of copper sulfate urine tests, but not with glucose enzymatic urine sugar tests. Diabetic patients may get false results.
|Probenecid side effects|
|Why Generic Probenecid should not be prescribed?
Generic Probenecid should not be used by patients suffering from life long inherited blood diseases, which can cause a variety of symptoms, including mental health problems (porphyrias).
Patients suffering from blood disorders, severe kidney disease and acute gout should not use Generic Probenecid.
Generic Probenecid should not be used if you are allergic to one or any of its ingredients. Please inform your doctor or pharmacist if you have previously experienced such an allergy.
If you feel you have experienced an allergic reaction, stop using Generic Probenecid and inform your doctor or pharmacist immediately.
Possible Generic Probenecid Side effects
More common side effects of Generic Probenecid may include:
Less common side effects of Generic Probenecid may include:
Rare side effects of Generic Probenecid may include:
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