About Quinine Sulfate
Buy Quinine Sulfate
Drug Class: What is Quinine ? and why is it prescribed?
Drug Mechanism: How does Quinine work?
Quinine Dosage: How should you take Quinine
Possible food and drug interactions when taking Quinine
Special information on Quinine
Quinine side effects
|Drug Class: What is Quinine ? and why is it prescribed?|
|Quinine is used to prevent and treat malaria.This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information. Quinine also is used to treat nighttime leg muscle cramps. Talk to your doctor about the possible risks of using this drug for your condition.|
|Drug Mechanism: How does Quinine work?|
|Antiprotozoal - The precise mechanism of action of quinine in malaria has not been determined but may be based on its ability to concentrate in parasitic acid vesicles, causing an elevation of pH in intracellular organelles. This is thought to disrupt the intracellular transport of membrane components and macromolecules, and phospholipase activity. Quinine has a schizonticidal action. Its ability to concentrate in parasitized erythrocytes may account for its selective toxicity against the erythrocytic stages of the four malarial parasites, including Plasmodium falciparum strains resistant to chloroquine. The drug is also gametocidal against Plasmodium vivax and Plasmodium malariae. Antimyotonic - Quinine increases the refractory period of skeletal muscle by direct action on the muscle fiber and the distribution of calcium within the muscle fiber, thereby diminishing the response to tetanic stimulation. It also decreases the excitability of the motor end-plate region, reducing the responses to repetitive nerve stimulation and to acetylcholine.|
|Quinine Dosage: How should you take Quinine|
|Quinine comes in capsules and tablets to take by mouth. It usually is taken three times a day (every 8 hours) for 3 days for malaria attacks, twice a day for 6 weeks to prevent or suppress malaria, and at bedtime for leg cramps. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take quinine exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor. if you miss a dose: Take the missed dose as soon as you remember it, and take any remaining doses for that day at evenly spaced intervals. However, if you take only one dose per day at bedtime, skip the missed dose completely. Do not take a double dose to make up for a missed one. Quinine: storage conditions Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication. Recommended dosage: Resistant malaria Adults 600mg thrice a day for 7 days Children 10mg/kg max dose: 2g/day every 8 hours Nocturnal leg cramps: Adults 200-600mg of quinine sulfate every night. Discontinue after several cramp-free nights.|
|Possible food and drug interactions when taking Quinine|
| Before taking quinine, tell your doctor if you are taking any of the following medicines:
|Special information on Quinine|
Most inportant fact about Quinine
Special precautions if you are pregnant or breast feeding
Special warnings about Quinine
Why Quinine should not be prescribed?
|Quinine side effects|
|If you experience any of the following serious side effects, stop taking quinine and seek emergency medical attention or contact your doctor immediately:
Since quinine is very bitter, do not chew tablets before swallowing them.
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