Drug Class: What is Sinequan ? and why is it prescribed?
Sinequan Mechanism: How does Sinequan work?
Sinequan Dosage: How should you take Sinequan
Possible food and drug interactions when taking Sinequan
Special information on Sinequan
Sinequan side effects
|Drug Class: What is Sinequan ? and why is it prescribed?|
|Sinequan is in a class of drugs called tricyclic antidepressants.
Sinequan affects chemicals in the brain that may become unbalanced and cause depression.
Sinequan is used to relieve symptoms of depression and anxiety such as feelings of sadness, worthlessness, or guilt; loss of interest in daily activities; changes in appetite; tiredness; sleeping too much; insomnia, and thoughts of death or suicide.
Sinequan is effective in treating people whose depression and/or anxiety is psychological, associated with alcoholism, or a result of another disease (cancer, for example) or psychotic depressive disorders (severe mental illness).
|Sinequan Mechanism: How does Sinequan work?|
|When depression occurs, there may be a decreased amount of the chemicals noradrenaline and serotonin released from nerve cells in the brain. When these chemicals are released from nerve cells they act to lighten mood. When they are reabsorbed into the nerve cells, they no longer have an effect on mood.
Sinequan works by preventing this re-absorption of noradrenaline and serotonin back into the nerve cells. Therefore, it helps prolong the mood-lightening effect of any released noradrenaline and serotonin. This helps relieve depression.
Sinequan also blocks receptors in other areas of the body resulting in side-effects such as drowsiness. Therefore, Sinequan may be particularly useful in the treatment of depression where sedation is required.
The full benefits of treatment with Sinequan may not appear for two to three weeks.
|Sinequan Dosage: How should you take Sinequan|
|Take Sinequan exactly as prescribed. It may take several weeks for you to feel better.
If you miss a Sinequan dose
If you are taking several doses a day, take the missed dose as soon as you remember, then take any remaining doses for that day at evenly spaced intervals. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Never take 2 doses at the same time.
If you are taking a single dose at bedtime and do not remember until the next morning, skip the dose. Do not take a double dose to make up for a missed one.
The optimum daily dosage of Sinequan depends on the condition which is being treated and the response of the individual.
The starting dose of Sinequan for mild to moderate illness is usually 75 milligrams per day. This dose can be increased or decreased by your doctor according to individual need. The usual ideal dose ranges from 75 milligrams per day to 150 milligrams per day, although it can be as low as 25 to 50 milligrams per day. The total daily dose can be given once a day or divided into smaller doses. If you are taking Sinequan once a day, the recommended dose is 150 milligrams at bedtime.
The 150-milligram capsule strength is intended for long-term therapy only and is not recommended as a starting dose.
For more severe illness, gradually increased doses of up to 300 milligrams may be required as determined by your doctor.
Once a satisfactory therapeutic response has been obtained, it is generally possible to reduce the dosage and still maintain this effect.
If you experience any of these symptoms, seek medical attention immediately. An overdose of Sinequan can be fatal.
Store Sinequan at room temperature.
Preparations of Sinequan
|Possible food and drug interactions when taking Sinequan|
Alcohol increases the danger in a Sinequan overdose.
Do not drink alcohol while taking Sinequan. Never combine Sinequan with drugs known as MAO inhibitors. Medications in this category include the antidepressants Nardil and Parnate. If you are switching from Prozac, wait at least 5 weeks after your last dose of Prozac before starting Sinequan. If Sinequan is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Sinequan with the following: Antidepressants that act on serotonin, such as Prozac, Zoloft, and Paxil Other antidepressants such as Elavil and Serzone Carbamazepine (Tegretol) Cimetidine (Tagamet) Clonidine (Catapres) Flecainide (Tambocor) Guanethidine (Ismelin) Major tranquilizers such as Compazine, Mellaril, and Thorazine Propafenone (Rythmol) Quinidine (Quinidex) Tolazamide (Tolinase)
|Special information on Sinequan|
|Most important fact about Sinequan
Serious, sometimes fatal, reactions have occurred when Sinequan is used in combination with drugs known as MAO inhibitors, including the antidepressants Nardil and Parnate. Any drug of this type should be discontinued at least 2 weeks prior to starting treatment with Sinequan, and you should be carefully monitored by your doctor.
Use caution when driving, operating machinery, or performing other hazardous activities. Sinequan may cause drowsiness or dizziness. If you experience drowsiness or dizziness, avoid these activities.
If you are taking any prescription or nonprescription drugs, consult your doctor before taking Sinequan.
Special precautions if you are pregnant or breastfeeding
Always inform your doctor if you are pregnant or planning a pregnancy, before using Sinequan.
It is not known whether Sinequan will be harmful to an unborn baby. Do not take Sinequan without first talking to your doctor if you are pregnant or could become pregnant during treatment.
Sinequan passes into breast milk and may affect a nursing baby. Do not take Sinequan without first talking to your doctor if you are breast-feeding a baby.
Special warnings about Sinequan
Notify your doctor or dentist that you are taking Sinequan if you have a medical emergency, and before you have surgery or dental treatment.
Treatment with Sinequan should not be stopped suddenly, but withdrawn gradually according to directions from your doctor. Abrupt withdrawal may cause symptoms such as nausea, vomiting, loss of appetite, headache, giddiness, chills, insomnia or anxiety.
|Sinequan side effects|
|Why Sinequan should not be prescribed?
Sinequan should not be used if you are allergic to one or any of its ingredients. Please inform your doctor or pharmacist if you have previously experienced such an allergy.
If you feel you have experienced an allergic reaction, stop using Sinequan and inform your doctor or pharmacist immediately.
Do not take Sinequan if you have the eye disorder known as glaucoma or difficulty in urinating unless you are directed to do so by your doctor.
Possible Sinequan side effects
The most common side effect of Sinequan is drowsiness.
Less common or rare side effects of Sinequan may include:
Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.
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