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Drug Class: What is Nexium and why is it prescribed?
Drug Mechanism: How does Nexium work?
Dosage: How should you take Nexium?
Possible food and drug interactions when taking Nexium
Special information on Nexium
Nexium side effects
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| Drug Class: What is Nexium and why is it prescribed? | ||
| Generic Nexium, Esomeprazole is in a class of drugs called proton pump inhibitors
(PPIs), which block the production of acid, by the stomach. Other drugs in the
same class include omeprazole (Prilosec), lansoprazole (Prevacid),
rabeprazole (Aciphex) and pantoprazole (Protonix). Chemically, Generic Nexium (esomeprazole)
is very similar to omeprazole. Proton pump inhibitors are used for the treatment
of conditions such as stomach and duodenal ulcers, gastroesophageal reflux disease
(GERD) and the Zollinger-Ellison syndrome which all are caused by stomach acid.
Generic Nexium relieves heartburn and other symptoms caused by the backflow of stomach acid into the canal to the stomach (the esophagus)--a condition known as gastroesophageal reflux disease. Generic Nexium is also prescribed to heal the damage (erosive esophagitis) that reflux disease can cause. Prescribed in combination with the antibiotics Biaxin and Amoxil, Generic Nexium is also used to treat the infection that causes most duodenal ulcers (ulcers occurring just beyond the exit from the stomach). Like its sister drug Prilosec, Generic Nexium works by reducing the production of stomach acid. |
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| Drug Mechanism: How does Nexium work? | ||
| Generic Nexium (Esomeprazole), like other proton-pump inhibitors, blocks the enzyme in the wall of the stomach that produces acid. By blocking the enzyme, the production of acid is decreased, and this allows the stomach and esophagus to heal.
Generic Nexium (Esomeprazole) was approved by the FDA in February, 2001. |
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| Dosage: How should you take Nexium? | ||
| Take Generic Nexium dosage at least one hour before meals. Be careful to swallow
it whole. If you have trouble swallowing Generic Nexium capsules, you can open
the capsule and carefully pour the pellets onto one tablespoon of applesauce.
The applesauce should not be hot. Mix in the pellets, then swallow the applesauce
immediately, without chewing. Generic Nexium dosage for adults Gastroesophageal Reflux Disease (GERD) For relief of symptoms, the usual Generic Nexium dosage is one 20-milligram capsule daily for 4 weeks. If symptoms persist, your doctor may prescribe an additional 4 weeks of Generic Nexium therapy. Erosive Esophagitis To heal damage, the Generic Nexium dosage is 20 or 40 milligrams of Generic Nexium once daily for 4 to 8 weeks. If you have not fully healed after 8 weeks, your doctor may prescribe an additional 4 to 8 weeks of therapy. To maintain healing, the Generic Nexium dosage is 20 milligrams once daily. Duodenal Ulcers As part of a three-drug treatment to rid the body of ulcer-causing H. Pylori bacteria, Generic Nexium is prescribed at a dosage of 40 milligrams once daily for 10 days. If you have severe liver problems, you should take no more than 20 milligrams of Generic Nexium per day. Generic Nexium Overdose: Any medication taken in excess can have serious consequences. Although no overdoses of Generic Nexium have been reported, the symptoms are expected to be like those of an overdose with the similar drug Prilosec. If you suspect an overdose of Generic Nexium, seek medical attention immediately. Symptoms of Generic Nexium overdose: May include blurred vision, confusion,
drowsiness, dry mouth, flushing, headache, nausea, rapid heartbeat, sweating
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| Possible food and drug interactions when taking Nexium | ||
| If Generic Nexium is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Generic Nexium with the following:
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| Special information on Nexium | ||
Special information if you are pregnant or breastfeeding: The effects of Generic Nexium
during pregnancy have not been adequately studied. If you are pregnant or plan
to become pregnant, check with your doctor. |
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| Nexium side effects | ||
| Side effects of Generic Nexium cannot be anticipated. If any develop or change
in intensity, inform your doctor as soon as possible. Only your doctor can determine
if it is safe for you to continue taking Generic Nexium. More common side effects of Generic Nexium: abdominal pain, diarrhea, headache. Rare side effects of Generic Nexium: abnormal sense of smell, acne, allergic reaction, anemia, apathy, back pain, black stools, blood disorders, blood in urine, burping, change in bowel habits, chest pain, chills, confusion, constipation, coughing, cramps, difficulty breathing, difficulty swallowing, dizziness, dry mouth, ear infection, earache, enlarged abdomen, enlarged thyroid gland, eye infection, facial swelling, fast or irregular heartbeat, fatigue, fever, flu-like symptoms, flushing, frequent or increased urination, fungal infections, general feeling of illness, hernia, hiccups, high blood pressure, hives, hot flushes, impotence, inability to sleep, increased appetite, indigestion, itching, leg and body swelling, liver problems, loss of appetite, loss of taste, lymph node problems, menstrual problems, migraine, mouth and throat problems, nausea, nervousness, nosebleed, pain, painful joints and muscles, painful urination, prickly or burning sensation, rash, rectal problems, rigidity, ringing in the ears, runny nose, sensitivity to touch, sinus problems, sleep disorders, sleepiness, sore throat, stomach bleeding, stomach pain, stomach upset, sweating, swelling, taste changes, thirst, tremors, urinary tract infection, vaginitis, vertigo, vision changes, vomiting, weakness, weight changes, worsening of arthritis, worsening of asthma, worsening of depression. |
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