What other drugs will affect indomethacin?
Before taking indomethacin, tell your doctor if you are taking any of the following drugs:
- aspirin or another salicylate (form of aspirin) such as salsalate (Disalcid), diflunisal (Dolobid), choline salicylate-magnesium salicylate (Trilisate, Tricosal, others), and magnesium salicylate (Doans, others),
- another nonsteroidal anti-inflammatory drug (NSAID) such as diclofenac (Cataflam, Voltaren), etodolac (Lodine), fenoprofen (Nalfon), flurbiprofen (Ansaid), ibuprofen (Motrin, Advil, others), ketoprofen (Orudis, Orudis KT), ketorolac (Toradol), meloxicam (Mobic), nabumetone (Relafen), naproxen (Aleve, Naprosyn, Anaprox, others), oxaprozin (Daypro), piroxicam (Feldene), sulindac (Clinoril), or tolmetin (Tolectin),
- an over-the-counter cough, cold, allergy, or pain medicine that contains aspirin, ibuprofen, indomethacin, or ketoprofen,
- an anticoagulant (blood thinner) such as warfarin (Coumadin),
- a steroid such as prednisone (Deltasone),
- insulin or an oral diabetes medicine such as glipizide (Glucotrol), glyburide (Diabeta, Micronase), and others,
- probenecid (Benemid),
- lithium (Eskalith, Lithobid, others), or
- bismuth subsalicylate in drugs such as Pepto-Bismol.
You may not be able to
take indomethacin, or you may require a dosage adjustment or special monitoring during treatment if you are taking any of the medicines listed above. Drugs other than those listed here may also interact with indomethacin. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including vitamins, minerals, and herbal products.