Imipramine is an antidepressant. Imipramine is a member of the family of drugs called tricyclic antidepressants.

Imipramine is also used on a short-term basis, along with behavioral therapies, to treat bed-wetting in children aged 6 and older. Imipramine s effectiveness may decrease with longer use.

Some doctors also prescribe Imipramine to treat bulimia, attention deficit disorder in children, obsessive-compulsive disorder,

Imipramine belongs to a group of medicines known as tricyclic antidepressants (TCA).

When depression occurs, there may be a decreased amount of the chemicals noradrenaline and serotonin released from nerve cells in the brain. When these chemicals are released from nerve cells they act to lighten mood. When they are reabsorbed into the nerve cells, they no longer have an effect on mood.

Imipramine works by preventing this re-absorption of noradrenaline and serotonin back into the nerve cells. Therefore, it helps prolong the

Imipramine may be taken with or without food.

You should not take Imipramine with alcohol.

Do not stop taking Imipramine if you feel no immediate effect. It can take from 1 to 3 weeks for improvement to begin.

Imipramine can cause dry mouth. Sucking hard candy or chewing gum can help this problem.

Adults
The usual starting dose of Imipramine is 75 milligrams a day. The doctor may increase this to 150 milligrams a day. The maximum daily dose is 200 milligrams.

Children

Imipramine should not be taken with a monoamine oxidase inhibitor (MAOI) antidepressant. Treatment with Imipramine should not be started until 3 weeks after stopping a MAOI. Conversely, treatment with a MAOI should not be started until 3 weeks after stopping Imipramine. Imipramine should also not be taken with moclobemide.

Imipramine blood levels may be increased by:

• Alprazolam
• Anti-psychotic medication such as chlorpromazine
• Cimetidine
• Top | Read More on Possible food and drug interactions with Imipramine
  
  

Most Important Fact about Imipramine
Serious, sometimes fatal, reactions have been known to occur when drugs such as Imipramine are taken with another type of antidepressant called an MAO inhibitor. Drugs in this category include Nardil and Parnate. Do not take Imipramine within 2 weeks of taking one of these drugs.

Imipramine precautions if you are pregnant or breastfeeding
Imipramine should not be used during pregnancy. Seek medical advice from your doctor.

Imipramine

• dizziness,
• drowsiness,
• dryness of mouth,
• headache,
• increased appetite,
• nausea,
• tiredness or weakness (mild),
• unpleasant taste,
• weight gain

Less common side effects of Imipramine may include:

• diarrhea,
• heartburn,
• increased sweating,
• trouble in sleeping,
• vomiting

Rare side