Grisactin belongs to the group of medicines called antifungals. Grisactin is used to treat fungus infections of the skin, hair, fingernails, and toenails. Grisactin may be taken alone or used along with medicines that are applied to the skin for fungus infections.

Grisactin is used to treat fungal infections of the skin, hair and nails. When given by mouth Grisactin concentrates itself in keratin, a protein which is present in all of these areas. Grisactin is thought to work by interfering with fungal cell growth and replication. Grisactin does not kill an established fungal infection but instead prevents infection of new keratin in these areas.

Grisactin is frequently used to treat fungal infections of the nail bed and ringworm

To minimize stomach irritation and help your body absorb the drug, take Grisactin at meal times or with food or whole milk. If you are on a low fat diet, check with your doctor.

Observe good hygiene during treatment to help control infection and prevent re-infection.
The usual treatment periods for various ringworm infections are:

• Ringworm of the scalp-4 to 6 weeks
• Ringworm of the body-2 to 4 weeks
• Athlete s foot-4 to 8 weeks

The usual treatment period, depending on the rate of growth, for ringworm

Blood thinning medications such as nicoumalone and warfarin are both broken down by Grisactin at a faster rate, and so there is an increased risk of a blood clot developing.

Absorption of Grisactin is reduced from the gut by phenobarbital (antiepileptic).

Grisactin may decrease the blood levels of cyclosporin.

Grisactin reduces the effectiveness of the oral contraceptives when taken in combination.

Tell your prescriber or health care professional about all other medicines

Most Important Fact about Grisactin
To clear up your infection completely, continue taking Grisactin as prescribed until your doctor tells you to stop. Although some improvement may appear within a few days, you need to take Grisactin for an extended period.

Grisactin precautions if you are pregnant or breastfeeding
Grisactin should not be used during pregnancy. The birth of twins that were joined together has been reported, although rarely, in women who took Grisactin

More common side effects of Grisactin may include:

• difficulty sleeping
• dizziness
• flatulence (gas),
• headache
• nausea, vomiting
• stomach pain

Less common side effects of Grisactin may include:

• dark yellow or brown urine
• confusion
• increased sensitivity to the sun or ultraviolet light
• loss of appetite
• mouth sores
• skin rash, redness, blistering, or peeling of skin
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