Drug Class: What is Glucophage XL and why is it prescribed?
Drug Mechanism: How does Glucophage XL work?
Dosage: How should you take Glucophage XL?
Possible food and drug interactions when taking Glucophage XL
Special information on Glucophage XL
Glucophage XL side effects
|Drug Class: What is Glucophage XL and why is it prescribed?|
| Glucophage XL, Metformin is an oral anti-diabetic medication used to treat
type 2 (non-insulin-dependent) diabetes (formerly adult-onset). Metformin is
not used to treat type 1 (insulin- dependent) diabetes (formerly juvenile-onset).
Diabetes develops when the body proves unable to burn sugar and the unused sugar builds up in the bloodstream. Glucophage lowers the amount of sugar in your blood by decreasing sugar production and absorption and helping your body respond better to its own insulin, which promotes the burning of sugar. It does not, however, increase
|Drug Mechanism: How does Glucophage XL work?|
| Metformin XL helps your body to regulate the amount of glucose (sugar) in your blood.
Insulin is a hormone produced by the pancreas that lowers glucose levels in blood by reducing the amount of glucose made by the liver and by increasing the removal of glucose from the blood by muscle and fat tissues. Diabetes results because of reduced production of insulin and reduced uptake (and effects) of insulin on the body &cotes s tissues.
Metformin acts by increasing the sensitivity of liver, muscle, fat, and other tissues to the uptake and effects of insulin. These actions lower
|Dosage: How should you take Glucophage XL?|
| Do not take more or less of this medication than directed by your doctor. The drug should be taken with food to reduce the possibility of nausea or diarrhea, especially during the first few weeks of therapy.
If taking Glucophage XR, be sure to swallow the tablet whole; do not crush it or chew it. The inactive ingredients in the tablet may occasionally appear in the stool. This is not a cause for concern.
Your doctor will tailor your dosage to your individual needs.
Glucophage: The usual starting dose is one 500-milligram tablet twice a day,
|Possible food and drug interactions when taking Glucophage XL|
| If Glucophage XL is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Glucophage with the following:
Amiloride (Moduretic), Calcium channel blockers (heart medications) such as Calan, Isoptin, and Procardia, Cimetidine (Tagamet), Decongestant, airway-opening drugs such as Sudafed and Ventolin, Digoxin (Lanoxin), Estrogens such as Premarin, Furosemide (Lasix), Isoniazid (Rifamate), a drug used for tuberculosis, Major tranquilizers such as Thorazine, Morphine,
|Special information on Glucophage XL|
| Special information if you are pregnant or breastfeeding:
If you are pregnant or plan to become pregnant, tell your doctor immediately. Glucophage XL should not be taken during pregnancy. Since studies suggest the importance of maintaining normal blood sugar (glucose) levels during pregnancy, your doctor may prescribe insulin injections instead.
It is not known whether Glucophage XL appears in human breast milk. Therefore, women should discuss with their doctors whether to discontinue the medication or to stop breastfeeding. If the medication is discontinued and if diet alone does not
|Glucophage XL side effects|
| Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Glucophage XL.
If side effects from Glucophage XL occur, they usually happen during the first few weeks of therapy. Most side effects are minor and will go away after you ve taken Glucophage for a while.
More common side effects may include: Abdominal discomfort, diarrhea, gas, headache, indigestion, nausea, vomiting, weakness.
Less common side effects may include: Abdominal
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