Possible food and drug interactions when taking Glipizide XL

It is essential that you closely follow your physician dietary guidelines and that you inform your physician of any medication, either prescription or nonprescription, that you are taking. Specific medications that affect Glipizide include:

• Airway-opening drugs such as Sudafed
• Antacids such as Mylanta
• Aspirin
• Chloramphenicol (Chloromycetin)
• Cimetidine (Tagamet)
• Clofibrate (Atromid-S)
• Corticosteroids such as prednisone (Deltasone)
• Diuretics such as HydroDIURIL
• Estrogens such as Premarin
• Fluconazole (Diflucan)
• Gemfibrozil (Lopid)
• Heart and blood pressure medications called beta blockers such as Tenormin and Lopressor
• Heart medications called calcium channel blockers such as Cardizem and Procardia XL
• Isoniazid (Rifamate, Rimactane)
• Itraconazole (Sporanox)
• MAO inhibitors (antidepressant drugs such as Nardil and Parnate)
• Major tranquilizers such as Thorazine and Mellaril
• Miconazole (Monistat)
• Nicotinic acid (Nicobid)
• Nonsteroidal anti-inflammatory drugs such as Motrin and Naprosyn
• Oral contraceptives
• Phenytoin (Dilantin)
• Probenecid (Benemid)
• Rifampin (Rifadin)
• Sulfa drugs such as Bactrim and Septra
• Thyroid medications such as Synthroid
• Warfarin (Coumadin).

Alcohol must be used carefully, since excessive alcohol consumption can cause low blood sugar.