Labetalol is in a class of drugs called beta-blockers. Beta-blockers affect the heart and circulatory system (arteries and veins). Labetalol is used to treat hypertension (high blood pressure).
Labetalol may also be used for purposes other than those listed in this medication guide.

Before taking labetalol, tell your doctor if you have

• asthma,
• a heart problem such as low blood pressure, a slow heart rate, heart block, sick sinus syndrome, a pacemaker, heart failure, and others,
• diabetes,
• depression,
• thyroid disease,
• kidney disease,
• liver disease, or
• any type of circulatory disease.

You may not be able to take labetalol, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions

Take labetalol exactly as directed by your doctor. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you.

Take each labetalol dose with a full glass of water.
Take labetalol with food or immediately following a meal.

Take labetalol at the same time every day whenever possible.

Do not stop taking labetalol without first talking to your doctor. Stopping abruptly may make your condition worse.

Store labetalol

If you experience any of the following serious side effects stop taking labetalol and call your doctor immediately or seek emergency medical treatment:

• an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face hives),
• wheezing or shortness of breath,
• an unusually slow or irregular heart beat,
• swelling of the feet and lower legs,
• leg pain or cramping,
• sudden weight gain (more than 2 pounds in one day or 5 pounds in one week),
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Before taking labetalol, tell your doctor if you are taking

• a heart medication such as nifedipine (Procardia, Adalat), reserpine (Serpasil), verapamil (Calan, Verelan, Isoptin), diltiazem (Cardizem, Dilacor XR), clonidine (Catapres), digoxin (Lanoxin), doxazosin (Cardura), guanadrel (Hylorel), prazosin (Minipress), or terazosin (Hytrin),
• a diabetes medication such as insulin, glyburide (Diabeta, Micronase, Glynase), glipizide (Glucotrol), chlorpropamide (Diabinese), or metformin (Glucophage),
• a nonsteroidal anti-inflammatory drug (NSAID)
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