Primidone slows down the brain and nervous system. Primidone reduces or controls seizures or convulsions in certain types of epilepsy, except for absence (petit mal) seizures.

Primidone contains the active ingredient primidone, which is an antiepileptic medicine. Primidone\'s activity results partly from the action of primidone itself, and partly from its breakdown products, phenobarbital (phenobarbitone) and phenylethylmalonamide (PEMA). It is not fully understood how much of a role each of the three plays in the overall antiepileptic effect of Primidone .

The central nervous system is made up of many nerve cells that communicate with each other through

Take Primidone exactly as prescribed. Do not change from one manufacturer\'s product to another without consulting your doctor.

Adults
For people 8 years of age and older who have not been treated before, the doctor will start Primidone as follows, using either 50-milligram or scored 250-milligram Primidone tablets:

Days 1 to 3: 100 to 125 milligrams at bedtime

Days 4 to 6: 100 to 125 milligrams 2 times a day

Days 7 to 9: 100 to 125 milligrams 3 times a day

Day 10 to maintenance: 250 milligrams 3 times a day

When Primidone is taken with phenytoin there may be increased conversion of Primidone to phenobarbital, leading to increased phenobarbital levels.

Primidone may reduce the effectiveness of oral contraceptives. Breakthrough bleeding may also occur.

There may be increased drowsiness if Primidone is taken with alcohol or medicines, which cause sedation such as: -

• antidepressants e.g. amitriptyline
• anxiolytics e.g. diazepam
• antipsychotics e.g. chlorpromazine
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Most Important Fact about Primidone
Primidone should not be stopped suddenly; this could cause you to have seizures. If you no longer need the medication, your doctor will reduce the dosage gradually

Primidone precautions if you are pregnant or breastfeeding
Although the effects of Primidone in pregnancy and nursing infants are not known, recent studies show an increase in birth defects in infants born to epileptic women taking anticonvulsant medications. Although most pregnant women taking anticonvulsant

More common side effects of Primidone may include :

• lack of muscle coordination,
• vertigo or
• severe dizziness

Less common side effects of Primidone may include:

• double vision,
• drowsiness,
• emotional disturbances,
• excessive irritability,
• fatigue,
• impotence,
• loss of appetite,
• nausea,
• skin eruptions that resemble measles,
• uncontrolled movement of the eyeballs,
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