Spironolactone+Hydrochlorothiazide is used in the treatment of high blood pressure and other conditions that require the elimination of excess fluid from the body. These conditions include congestive heart failure, cirrhosis of the liver, and kidney disease.

Spironolactone+Hydrochlorothiazide combines two diuretic drugs that help your body produce and eliminate more urine.

Spironolactone, one of the ingredients, helps to minimize the potassium loss that can

Spironolactone belongs to a group of medications known as the potassium-sparing diuretics.

Spironolactone acts in the kidney to remove excess water from the blood into the urine.

Spironolactone blocks the actions of a hormone called aldosterone, which causes an increase in the removal of salts such as sodium from the blood. This removal of salts causes water to be drawn out of the blood and into the kidneys, where it is then excreted in the urine. Removing water from the blood causes a decrease

Take Spironolactone+Hydrochlorothiazide exactly as prescribed. Stopping Spironolactone+ Hydrochlorothiazide suddenly could cause your condition to worsen.

Adults
Congestive Heart Failure, Cirrhosis, Nephrotic Syndrome (kidney disorder)

The usual dose of is 25 milligrams each of Spironolactone and Hydrochlorothiazide daily, taken as a single dose or in divided doses. Dosage may range from 25 milligrams to 50 milligrams of each ingredient

The following drugs should not be taken with Spironolactone+Hydrochlorothiazide

• alcohol
• allopurinol
• amantadine
• amphotericin B
• antiinflammatory drugs including NSAIDs (e.g., ibuprofen), aspirin, or salicylates
• arsenic trioxide
• barbiturate medicines for inducing sleep or treating seizures (convulsions)
• bepridil
• caffeine; ergotamine
• cisplatin
• cyclosporine
• diazoxide
• digoxin
• dofetilide
• drospirenone;
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Most Important Fact about Spironolactone+Hydrochlorothiazide
If you have high blood pressure, you must take Spironolactone+Hydrochlorothiazide regularly for it to be effective. Since blood pressure declines gradually, it may be several weeks before you get the full benefit of Spironolactone+Hydrochlorothiazide ; and you must continue taking Spironolactone+Hydrochlorothiazide even if you are feeling well. Spironolactone+ Hydrochlorothiazide does not cure high blood pressure;

More common side effects of Spironolactone+Hydrochlorothiazide may include:

• breast tenderness in females
• constipation
• decreased appetite
• dizziness or lightheadedness
• dry mouth
• fatigue or weakness
• increased frequency of urination
• increased sensitivity to the sun
• irregular menstrual periods
• inability to have an erection
• somach upset, pain, or cramps,
• indigestion

Less common or rare side