Tiotropium Rotacaps +Handihaler is an anticholinergic medication. Tiotropium Rotacaps+ Handihaler prevents narrowing of the airways.

Tiotropium Rotacaps + Handihaler is used in the treatment of bronchospasm associated with chronic obstructive pulmonary disease (COPD) such as chronic bronchitis and emphysema.

Tiotropium Rotacaps+Handihaler works in the lungs, where it blocks receptors called muscarinic receptors that are found on the muscle surrounding the airways. A natural chemical called acetylcholine normally acts on these receptors, causing the muscle in the airways to contract and the airways to narrow.

In chronic obstructive lung diseases (COPD), such as chronic bronchitis or emphysema, the airways are very narrowed, and this makes breathing in and out difficult.

Tiotropium Rotacaps+Handihaler blocks the muscarinic receptors in the lungs

Do not swallow Tiotropium Rotacaps+Handihaler by mouth. The contents of the capsule are inhaled using a special inhaler, usually once daily as directed.

Do not breathe into the mouthpiece at any time. Do not use Tiotropium Rotacaps+Handihaler more often than prescribed. Carefully read the patient instruction sheet in the product package, and learn how to properly use the special inhaler device.

Consult your doctor or pharmacist if you are unclear about any of the information. It may take several days before full benefits occur. For best results,

Tiotropium Rotacaps+Handihaler can be successfully taken with the following:

• sympathomimetic bronchodilators, such as salbutamol and terbutaline
• theophylline and aminophylline
• corticosteroids taken by mouth, e.g. prednisolone, or by inhaler, e.g. beclometasone, budesonide.

Tiotropium Rotacaps+Handihaler has not been studied in combination with other anticholinergic medicines such as those below, and these are therefore not recommended while you are taking Tiotropium Rotacaps+Handihaler

Most Important Fact about Tiotropium Rotacaps+Handihaler
Do not suddenly stop taking Tiotropium Rotacaps+Handihaler without consulting your doctor. If your condition persists or worsens, contact your doctor or pharmacist.

Tiotropium Rotacaps+Handihaler precautions if you are pregnant or breastfeeding
The safety of Tiotropium Rotacaps + Handihaler in pregnancy has not been established. It should therefore be used with caution during pregnancy, and only if the benefits to the mother outweigh any risks to

More common side effects of Tiotropium Rotacaps+Handihaler may include:

• dry mouth
• dry throat
• cough
• fast heart beat
• blurred vision
• high pressure in the eye (glaucoma)

Less common or rare side effects of Tiotropium Rotacaps+Handihaler may include:

• constipation
• difficulty in passing urine
• swollen tongue and lips,
• mouth ulcers,
• rash on the face
• a change in heart rate