Trental CR (Pentoxifylline) improves blood flow by making the red blood cells more flexible and by thinning the blood.

Trental CR (Pentoxifylline) helps to decrease the pain, discomfort, or cramps you can get from having poor circulation in your leg veins.

Trental CR (Pentoxifylline) works by increasing the supply of oxygen to the tissues. Trental CR does this by causing the blood vessels to widen, resulting in increased blood supply. Trental CR also has effects on the blood cells, which results in a thinning of the blood, allowing it to pass more easily through the blood vessels.

Both these effects are useful in peripheral vascular disease, where the blood vessels in the extremities are narrowed. Trental CR reduces the pain of peripheral vascular

Take Trental CR capsules orally. Swallow the capsules whole with a drink of water; do not break open or chew. You can take Trental CR with food or antacids if it upsets your stomach. Take your Trental CR doses at regular intervals. Do not take Trental CR more often than directed.

Adults
The usual dosage of Trental in controlled-release tablets is one 400-milligram tablet 3 times a day with meals.

While the effect of Trental CR may be seen within 2

The following drugs may interact with Trental CR

• cimetidine
• ciprofloxacin
• medicines for diabetes
• some herbal supplements, like garlic, ginger or ginkgo biloba
• theophylline
• warfarin

Inform your health care professional about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if

Most Important Fact about Trental CR
Trental CR can ease the pain in your legs and make walking easier but should not replace other treatments such as physical therapy or surgery.

Trental CR precautions if you are pregnant or breastfeeding
The safety of Trental CR during pregnancy has not been established. The manufacturer therefore advises that it should be avoided during pregnancy. Seek medical advice from your doctor.

Trental CR passes into breast milk in small amounts. The

More common side effects of Trental CR may include:

• agitation
• chest pain,
• fast or irregular heartbeat (palpitations)
• drowsiness
• flushing
• seizures (convulsions)

Less common or rare side effects of Trental CR may include:

• dizziness
• headache
• indigestion
• nausea,
• vomiting