Drug class: What is zofran and why is it prescribed?
Drug Mechanism: How does it work?
Dosage: How should you take this medication?
Possible food and drug interactions when taking this medication
Special information on Zofran
Zofran side effects
|Drug class: What is zofran and why is it prescribed?|
| Zofran is used for the prevention of nausea and vomiting caused by radiation therapy and chemotherapy for cancer, and, in some cases, to prevent these problems following surgery.
To ensure the maximum effect, it is important to take all doses of Zofran exactly as prescribed by your doctor.
|Drug Mechanism: How does it work?|
|Ondansetron is a selective 5-HT 3 receptor antagonist. While its mechanism of action has not been fully characterized, ondansetron is not a dopamine-receptor antagonist. Serotonin receptors of the 5-HT 3 type are present both peripherally on vagal nerve terminals and centrally in the chemoreceptor trigger zone of the area postrema. It is not certain whether ondansetron s antiemetic action is mediated centrally, peripherally, or in both sites. However, cytotoxic chemotherapy appears to be associated with release of serotonin from the enterochromaffin cells of the small intestine.|
|Dosage: How should you take this medication?|
| Your doctor will tell you how much drug to take and how often, depending on the type of therapy you will be having.
Zofran is available in three forms: an oral solution, tablets that you swallow with water, and orally disintegrating tablets that can be swallowed with saliva alone (Zofran ODT). If you re taking the orally disintegrating tablets, dont remove them from the blister pack until it s time for a dose. Then peel off the foil backing with dry hands, gently remove the tablet, and immediately place it on your tongue. Do not attempt to push the tablets through
|Possible food and drug interactions when taking this medication|
|No interactions with Zofran have been reported.|
|Special information on Zofran|
| Special information if you are pregnant or breastfeeding:
The effects of Zofran during pregnancy have not been adequately studied. If you are pregnant or plan to become pregnant, inform your doctor immediately. Zofran may appear in breast milk and could affect a nursing infant. If Zofran is essential to your health, your doctor may advise you to discontinue breastfeeding until your treatment with this medication is finished.
Special warnings about Zofran
|Zofran side effects|
| Side effects of Zofran cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Zofran.
More common side effects of Zofran may include:
Constipation, diarrhea, dizziness, fatigue, headache.
Less common or rare side effects of Zofran may include:
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