Drug Class: What is Plavix ? and why Plavix is prescribed?
Plavix Mechanism: How does Plavix work?
Plavix Dosage: How should you take Plavix ?
Possible food and drug interactions when taking Plavix
Special information on Plavix
Plavix side effects
|Drug Class: What is Plavix ? and why Plavix is prescribed?|
|Generic Plavix, Clopidogrel is an anti-platelet drug, that is, a drug that inhibits the ability of platelets to clump together as part of a blood clot. Generic Plavix keeps blood platelets slippery and discourages formation of clots, thereby improving blood flow to your heart, brain, and body. Generic Plavix is prescribed to reduce the risk of heart attack, stroke, and serious circulation problems in people with hardening of the arteries or unstable angina (dangerous chest pain), and in people whove already suffered a heart attack or stroke.|
|Plavix Mechanism: How does Plavix work?|
|Generic Plavix, Clopidogrel works by preventing excessive blood clotting. Generic Plavix blocks a specific receptor, which in turn prevents fibrinogen from binding at those receptors. Fibrinogen is needed for a clot to form, and if it is not bound to its receptor, there is a decreased chance for clots to form in that area. Clopidogrel is similar to ticlopidine (Ticlid) in chemical structure and in the way it works. Unlike ticlopidine, clopidogrel does not cause serious reductions of white cells in the blood and, therefore, routine blood testing to determine if the white blood cell count is low is not necessary during treatment. The risk of heart attacks and strokes (which usually are caused by blood clots) is increased in patients with a recent history of stroke or heart attack and patients with peripheral vascular disease. (Peripheral vascular disease is the same as atherosclerotic arterial disease or hardening of the arteries in which the arteries become narrowed. It frequently occurs in the legs and often causes claudication or pain in the legs upon walking). Clopidogrel is used to reduce the risk of heart attacks and strokes in these patients. Clopidogrel was approved by the FDA in 1997.|
|Plavix Dosage: How should you take Plavix ?|
Generic Plavix can be taken with or without food.
ADULTS: The usual dose of Generic Plavix is 75 milligrams once a day. To give people with unstable angina an extra boost, their first dose of Generic Plavix is usually increased to 300 milligrams.
CHILDREN: The safety and effectiveness of Generic Plavix have not been established in children.
Generic Plavix Overdose: Any medication taken in excess can have serious consequences. If you suspect an overdose of Generic Plavix, seek medical attention immediately.
Potential symptoms of Generic Plavix overdose may include: Difficulty breathing, exhaustion, stomach or intestinal bleeding, vomiting.
If you miss a dose of Generic Plavix, take it as soon as you remember. If it is almost time for your next dose of Generic Plavix, skip the one you missed and go back to your regular schedule. Do not take 2 doses of Generic Plavix at the same time.
Generic Plavix Storage instructions: Store Generic Plavix at room temperature.
Generic Plavix Preparations: Generic Plavix Tablets available in 75 mg
|Possible food and drug interactions when taking Plavix|
Generic Plavix increases the clot-fighting effect of aspirin. The two drugs are often taken together, and combined treatment has lasted for up to one year.
If Generic Plavix is taken with certain other drugs, the effects of either could be increased, decreased, or altered. Ask your doctor before starting any new drug; and be doubly careful before combining Generic Plavix with the following:
|Special information on Plavix|
Special information if you are pregnant or breastfeeding: The effects of Plavix during pregnancy have not been adequately studied. If you are pregnant or plan to become pregnant, inform your doctor immediately. Use Plavix during pregnancy only if absolutely necessary. Do not breastfeed while taking Plavix, since Plavix may appear in breast milk.
Most Important Fact about Plavix: Because Plavix slows clotting, it will take longer than usual to stop bleeding. Be sure to report any unusual bleeding to your doctor immediately, and tell any doctor or dentist planning a procedure that you have been taking Plavix. You should discontinue Plavix 5 days before any kind of surgery.
|Plavix side effects|
Side effects of Generic Plavix cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue using Generic Plavix.
More common side effects of Generic Plavix may include: Abdominal pain, back pain, bronchitis, bruising and bleeding under the skin, chest pain, coughing, depression, diarrhea, difficulty breathing, dizziness, fatigue, fluid retention and swelling, flu symptoms, headache, high blood pressure, high cholesterol, indigestion, inflammation of the nasal passages, itching, joint pain, nausea, pain, purple discoloration of skin, rash, upper respiratory tract infection, urinary tract infection
Less common side effects of Generic Plavix may include: Anemia, anxiety, arthritis, cataracts, constipation, fainting, fever, gout, heart problems, hernia, increased heart rate, insomnia, irregular heartbeat, joint disease, leg cramps, loss of sensitivity to touch, nosebleed, pinkeye, pneumonia, skin problems, stomach and intestinal bleeding, skin tingling, sinus inflammation, vomiting, weakness
Rare side effects of Generic Plavix may include: Allergic reactions including swelling of the face and throat and difficulty breathing, bleeding in the eyes, confusion, decreased circulation in the skin, decreased white blood cell counts, excessive menstrual flow, fatal bleeding, hallucinations, kidney problems, liver problems, skin erruptions, stomach ulcers, taste disorders, wheezing, widespread internal bleeding
Why should Generic Plavix not be prescribed?
Do not take Generic Plavix if you have a bleeding stomach ulcer or bleeding in the area around the brain. Also avoid Generic Plavix if it gives you an allergic reaction.
Special warnings about Generic Plavix : If you have ever had a stomach ulcer or bleeding in the digestive tract, make sure the doctor is aware of it; Generic Plavix should be used with caution. Generic Plavix should also be used carefully if you suffer from problems inside the eyes, have bleeding problems due to severe liver disease, or expect to be at risk of bleeding from any other cause. In extremely rare cases (about 4 in a million), a dangerous bleeding problem called thrombotic thrombocytopenic purpura has been known to develop in patients taking Generic Plavix. Signs include fever and bleeding under the skin. Call your doctor immediately if you develop these symptoms.
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