Drug Class: What is Silvadene and why is it prescribed?
Silvadene cream Mechanism: How does Silvadene work?
Silvadene cream Dosage: How should you take Silvadene
Possible food and drug interactions when taking Silvadene
Special information on Silvadene
Silvadene side effects
|Drug Class: What is Silvadene and why is it prescribed?|
|Generic Silvadene Cream 1% is applied directly to the skin. The cream is used along with other medications to prevent and treat wound infections in people with second- and third-degree burns. Generic Silvadene is effective against a variety of bacteria as well as yeast.|
|Silvadene cream Mechanism: How does Silvadene work?|
The exact mechanism by which silver sulfadiazine exerts its antiinfective activity is unknown. Both free silver and the sulfonamide moiety may exert activity, but the drug does not inhibit folic acid synthesis as other sulfonamides do.
Generic Silvadene disrupts bacteria by damaging the cell membrane and the cell wall rather than by inhibiting folic acid synthesis. Generic Silvadene has a wide spectrum of bactericidal activity against both gram-positive and gram-negative organisms. Organisms that are susceptible to topical Generic Silvadene include Staphylococcus aureus, S. epidermidis, beta-hemolytic streptococci, Klebsiella, Escherichia coli, Enterobacter (including E. cloacae), Citrobacter, Proteus, Pseudomonas, Morganella morganii, Providencia, Serratia, and Candida albicans.
|Silvadene cream Dosage: How should you take Silvadene|
|Generic Silvadene cream is for external use only.
Bathe the burned area daily.
You should continue using Generic Silvadene Cream until the area has healed or is ready for skin grafting.
Clean your skin and apply Generic Silvadene with a sterile, gloved hand. Apply a thin layer (about one-sixteenth of an inch) to the affected area.
If you miss a Generic Silvadene dose
Apply Generic Silvadene Cream 1% to the affected area once or twice daily to a thickness of one-sixteenth of an inch. Treatment with Generic Silvadene should be continued until your doctor is satisfied that healing has occurred or determines that the burn site is ready for grafting.
Generic Silvadene Storage instructions
Generic Silvadene Overdose
|Possible food and drug interactions when taking Silvadene|
|If Generic Silvadene is used with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Generic Silvadene with the following:
Topical enzyme preparations such as Panafil and Santyl, that contain collagenase, papain, or sutilains.
|Special information on Silvadene|
|Most important fact about Generic Silvadene
Generic Silvadene is a sulfa derivative. If burn wounds cover extensive areas of the body, Generic Silvadene may be absorbed into the bloodstream, and if you have ever had an allergic reaction to sulfa drugs, such as Bactrim or Septra, this could lead to a similar reaction. Make sure your doctor is aware of any drug reactions you have experienced.
Special precautions if you are pregnant or breastfeeding
The safety of Generic Silvadene during pregnancy has not been fully studied, but you definitely should not take this drug at the end of your pregnancy, as it can lead to complications for the baby.
Although it is not known whether Generic Silvadene appears in breast milk, other sulfa drugs are excreted in breast milk and can cause harm to a nursing infant. If this medication is essential to your health, your doctor may advise you to stop breastfeeding until your treatment is finished.
Special warnings about Generic Silvadene
There is a small chance of fungal infection when using Generic Silvadene.
|Silvadene side effects|
|Why Generic Silvadene should not be prescribed?
You should not use Generic Silvadene if you are allergic to sulfa drugs such as Bactrim or Septra.
Do not use Generic Silvadene at the end of pregnancy, on premature infants, or on newborn infants during the first 2 months of life.
Possible Generic Silvadene side effects
Side effects of Generic Silvadene may include:
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