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Drug Class: What is Depakote and why is it prescribed?
Depakote Mechanism: How does Depakote work?
Depakote Dosage: How should you take Depakote
Possible food and drug interactions when taking Depakote
Special information on Depakote
Depakote side effects
|Drug Class: What is Depakote and why is it prescribed?|
|Generic Depakote can help with seizure (convulsion) control in certain types of epilepsy.
Generic Depakote is also used for other conditions, such as the prevention of migraines, and control of behavioral problems associated with dementia
|Depakote Mechanism: How does Depakote work?|
|Generic Depakote is used to treat certain types of seizures and convulsions.
Generic Depakote differs in structure from other antiepileptic drugs in common use. The way in which Generic Depakote works is not fully understood, but it appears to involve several mechanisms and to act on a variety of targets, probably accounting for its broad efficacy.
Generic Depakote may be prescribed alone or with other epilepsy medications.
An extended-release form of this drug, Generic Depakote ER, is prescribed to prevent migraine headaches.
|Depakote Dosage: How should you take Depakote|
Take Generic Depakote by mouth. Follow the directions on the prescription label. Swallow the tablets whole with a drink of water; do not crush or chew. If Generic Depakote upsets your stomach, take it with food or milk; do not take with carbonated drinks.
Dose of Generic Depakote for adults and children 10 years of age or older is determined by body weight. The usual recommended starting dose is 10 to 15 milligrams per 2.2 pounds per day, depending on the type of seizure. Your doctor may increase the dose at 1-week intervals by 5 to 10 milligrams per 2.2 pounds per day until your seizures are controlled or the side effects become too severe. The most you should take is 60 milligrams per 2.2 pounds per day. If your total dose of Generic Depakote is more than 250 milligrams a day, your doctor will divide it into smaller individual doses.
Older adults usually begin taking Generic Depakote at lower dosages, and the dosage is increased more slowly.
Generic Depakote ER works differently, so you cannot substitute one type for the other.
Researchers have not established the safety and effectiveness of Generic Depakote for prevention of migraines in children or in adults over 65.
If you miss a Generic Depakote dose
Generic Depakote Overdose
Symptoms of Generic Depakote overdose include
Generic Depakote Storage instructions
Store Generic Depakote at room temperature between 15 and 25 degrees C (59 and 77 degrees F). Keep container tightly closed. Throw away any unused amount of Generic Depakote after the expiration date.
Preparations of Generic Depakote:
|Possible food and drug interactions when taking Depakote|
Generic Depakote may increase the blood levels of the following medicines:-
Generic Depakote may increase the blood level of lamotrigine and may increase the risk of skin reactions associated with lamotrigine. Your doctor may need to reduce your lamotrigine dose.
Generic Depakote increases the blood levels of phenobarbitone, which may result in excessive sedation if these two medicines are taken together. The dose of phenobarbitone may need to be reduced by your doctor. Generic Depakote increases the blood levels of phenytoin and phenytoin levels should be monitored if these medicines are used together.
There may be increased sedation if Generic Depakote is taken with benzodiazepines.
There may be an increase in side effects such as dizziness, tiredness, blurred vision and vomiting if Generic Depakote is taken with carbamazepine.
The blood level of Generic Depakote may be increased by the following medicines:-
Mefloquine may decrease the blood level of Generic Depakote.
|Special information on Depakote|
|Most Important Fact about Generic Depakote
Generic Depakote can cause serious or even fatal liver damage, especially during the first 6 months of treatment. Children under 2 years of age are the most vulnerable, especially if they have certain other disorders such as mental retardation.
The risk of liver damage decreases with age; but you should always be alert for the following symptoms: loss of seizure control, weakness, dizziness, drowsiness, a general feeling of ill health, facial swelling, loss of appetite, vomiting, and yellowing of the skin and eyes. If you suspect a liver problem, call your doctor immediately.
Generic Depakote has also been known to cause life-threatening damage to the pancreas. This problem can surface at any time, even after years of treatment. Call your doctor immediately if you develop any of the following warning signs: abdominal pain, loss of appetite, nausea, or vomiting.
Generic Depakote precautions if you are pregnant or breastfeeding
Women who decide to continue taking Generic Depakote during a pregnancy should be prescribed Generic Depakote on its own, in the lowest effective dose, in doses that are split over the day, and if possible as a prolonged release brand. These measures can help minimize the risk to the baby. Specialist medical advice must be sought. Generic Depakote passes into breast milk in small amounts, but there have been no reports of harmful effects from this on nursing infants. Seek further medical advice from your doctor.
Special warnings about Generic Depakote
Generic Depakote may cause drowsiness. If affected do not drive or operate machinery.
There is no information regarding the safety and effectiveness of Generic Depakote to treat mania in children and adolescents under the age of 18 years.
Generic Depakote can cause some people to put on weight. Talk to your doctor about this before you start treatment so that you can discuss strategies, such as diet and exercise, for minimizing any weight gain.
People with diabetes should be aware that Generic Depakote could cause false positive results in urine tests for ketones.
Why Generic Depakote should not be prescribed?
If you feel you have experienced an allergic reaction, stop using Generic Depakote and inform your doctor or pharmacist immediately.
|Depakote side effects|
More common side effects of Generic Depakote may include:
More common side effects of Generic Depakote may include:
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