Drug Class: What is Spironolactone and why is it prescribed?
Drug Mechanism: How does it work?
Dosage: How should you take Spironolactone?
Possible food and drug interactions when taking Spironolactone
Special information on Spironolactone
Possible side effects of Spironolactone
|Drug Class: What is Spironolactone and why is it prescribed?|
Spironolactone is a blood pressure medication. It flushes excess salt and water from the body and controls high blood pressure. Spironolactone is used in the diagnosis and treatment of hyperaldosteronism, a condition in which the adrenal gland secretes too much aldosterone (a hormone that regulates the body s salt and potassium levels). Spironolactone is also used in treating other conditions that require the elimination of excess fluid from the body. These conditions include congestive heart failure,
|Drug Mechanism: How does it work?|
|One of the main functions of the kidneys is to retain salt (sodium chloride) and water. In patients with heart failure and cirrhosis, increased levels of a hormone produced by the adrenal glands, called aldosterone, causes salt and fluid retention by the kidneys. Spironolactone inhibits the action of aldosterone causing the kidneys to excrete salt and fluid while retaining potassium. Therefore, Spironolactone is classified as a potassium-sparing medication that promotes the output of urine (diuretic).|
|Dosage: How should you take Spironolactone?|
Take Spironolactone exactly as prescribed by your doctor. Stopping Spironolactone suddenly could cause your condition to worsen.
If you miss a dose:
|Possible food and drug interactions when taking Spironolactone|
If Spironolactone is taken with certain other drugs, the effects of either could be increased, decreased, or altered.
It is especially important to check with your doctor before combining Spironolactone with the following: ACE inhibitors such as Vasotec and Capoten, Alcohol, Barbiturates such as phenobarbital and Seconal, Digoxin (Lanoxin), Indomethacin (Indocin), Lithium (Lithonate), Narcotic drugs such as those containing codeine, Nonsteroidal anti-inflammatory drugs (NSAIDs) such as Advil, Aleve, and Motrin, Norepinephrine
|Special information on Spironolactone|
The effects of Spironolactone during pregnancy have not been adequately studied. If you are pregnant or plan to become pregnant, inform your doctor immediately.
Spironolactone appears in breast milk and could affect a nursing infant.
If Spironolactone medication is essential to your health, your doctor may advise you to discontinue breastfeeding until your treatment with this medication is finished. Potassium supplements or other diuretics that leave your potassium levels high, such as Maxzide, should not be
|Possible side effects of Spironolactone|
Side effects of Spironolactone cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Spironolactone.
Side effects may include:
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